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目的了解广州番禺地区2型糖尿病(T2DM)和糖尿病前期(PM)人群流行趋势,探讨与其相关的危险因素,为制定糖尿病综合干预对策提供依据。方法采用分层整群抽样的方法,调查广州市番禺区4 200人,调查方法包括实验室检查、体格检查和问卷调查。结果 PM和T2DM患者检出率分别为19.90%(836/4 200)和9.81%(412/4 200)。多因素Logistic回归分析显示,T2DM和PM患病率的主要影响因素为年龄(60~74岁:OR=3.805,95%CI:1.965~7.368),身体质量指数(>30 kg/m~2,OR=2.053,95%CI:1.421~2.966),职业为农(渔)民或离退休、家务及待业(OR=1.778,95%CI:1.209~2.615),有既往心脑血管疾病、血脂异常或外周血管病变史(OR=1.620,95%CI:1.182~2.209),居住在乡村(OR=1.513,95%CI:1.118~2.047),锻炼频率≥1次/周(OR=1.378,95%CI:1.022~1.860)者。结论T2DM和PM患病率较高,应广泛开展糖尿病相关危险行为综合干预,以降低T2DM和PM的发病率。
Objective To understand the prevalence of type 2 diabetes mellitus (T2DM) and pre-diabetes (PM) in Panyu, Guangzhou, and to explore the risk factors associated with them, so as to provide a basis for formulating a comprehensive intervention strategy for diabetes mellitus. Methods A stratified cluster sampling method was used to investigate 4 200 people in Panyu District of Guangzhou City. The investigation methods included laboratory examination, physical examination and questionnaire. Results The detection rates of PM and T2DM patients were 19.90% (836/4 200) and 9.81% (412/4 200) respectively. Multivariate logistic regression analysis showed that the main influencing factors of prevalence of T2DM and PM were age (60-74 years old: OR = 3.805, 95% CI: 1.965-7.368), body mass index (> 30 kg / OR = 2.053,95% CI: 1.421-2.966), and were employed as farmers or retired, domestic and unemployed (OR = 1.778, 95% CI: 1.209-2.615), with previous cardiovascular and cerebrovascular diseases, dyslipidemia (OR = 1.513, 95% CI: 1.118-2.04), exercise frequency ≥1 / week (OR = 1.378, 95% CI, CI: 1.022 ~ 1.860). Conclusions The prevalence of T2DM and PM is high. Comprehensive interventions should be carried out to reduce the incidence of T2DM and PM.