目的探讨儿童慢性唇炎与血微量元素的相关性,为慢性唇炎的治疗提供新的理论依据。方法收集2014年1月-2016年1月本院收治的189例慢性唇炎患儿作为观察组,选择同期健康儿童264例作为健康对照组。采用原子吸收光谱仪对2组儿童的血清钙、镁、锌、铁、铜元素进行测定并对比。结果慢性唇炎患儿血锌浓度为(77.03±12.58)μmol/L,明显低于健康对照组(89.36±13.22)μmol/L,差异有统计学意义(P<0.05),而血清中铜、铁、镁、钙水平与健康对照组相比,差异均无统计学意义(P>0.05)。2组不同性别儿童5种微量元素水平相比较,男、女儿童间5种微量元素差异均无统计学意义(P>0.05)。结论慢性唇炎患儿血锌水平偏低,慢性唇炎患儿应注意血清微量元素的检测,并及时纠正。对慢性唇炎患儿实施微量元素稳态调整可获得一定的干预效果。 Objective To explore the correlation between chronic cheilitis and blood trace elements in children and to provide a new theoretical basis for the treatment of chronic cheilitis. Methods A total of 189 children with chronic cheilitis admitted in our hospital from January 2014 to January 2016 were selected as observation group and 264 healthy children were selected as healthy control group. The contents of calcium, magnesium, zinc, iron and copper in two groups of children were measured and compared by atomic absorption spectrometer. Results The level of serum zinc in children with chronic cheilitis was (77.03 ± 12.58) μmol / L, which was significantly lower than that in healthy controls (89.36 ± 13.22) μmol / L, with statistical significance (P <0.05) There was no significant difference in iron, magnesium and calcium levels between healthy controls and control group (P> 0.05). There were no significant differences in the five trace elements between male and female children in the two groups (P> 0.05). Conclusion Children with chronic cheilitis have a low blood zinc level. Children with chronic cheilitis should pay attention to the detection of serum trace elements and correct them promptly. The implementation of trace elements in children with chronic cheilitis steady-state adjustment can get some intervention.