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以前工作中作者曾报告过,X线照射后注射人参提取物可提高小鼠30天活存率,加速血小板、红细胞计数及脾重和脾DNA含量的恢复。但是该物质有引起正常动物体重下降和脾增生的副作用。作者发现人參提取物加热处理得到的热稳定部份可以完全消除上述的副作用且盇羝浞阑ばЧ1疚墓鄄炝巳瞬翁崛∥锶任榷ú糠荻孕∈蟆⒋笫蠛碗嗍蟮姆阑ばвΑ?人参提取物按Oura等人方法得到,将其溶于生理盐水,弃去沉淀后,以稀碱中和之,在沸水中加热,第二次离心分离出上清部份即为热稳定部份。将人参提取物的重量减去两次沉淀的干重即为热稳定部份的重量。实验动物小鼠为ICR种,四周龄,雄性,大鼠为Wister种。4周龄,雄性;豚鼠为Hartley种,
In previous work, the authors have reported that injection of ginseng extract after X-ray irradiation can increase the survival rate of mice for 30 days, and accelerate the recovery of platelets, red blood cell counts, and spleen weight and spleen DNA content. However, this substance has side effects that cause normal animal body weight loss and splenic hyperplasia. The authors found that the heat-stable part of the heat treatment of ginseng extract can completely eliminate the above-mentioned side effects. The ginseng extract is obtained by Oura et al. and is dissolved in physiological saline. After discarding the precipitate, it is neutralized with dilute alkali and heated in boiling water. The supernatant is centrifuged a second time. The portion is the thermally stable part. The weight of the heat stable part is the weight of the ginseng extract minus the dry weight of the two precipitates. The experimental animals were ICR species, four weeks old, male, and the rats were Wister species. 4 weeks old, male; guinea pig Hartley species,