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目的：探讨在我国进行胰肾联合移植（ＳＰＫＴ）的可行方法，并应用于临床。方法：在８０余次尸体供者腹腔多脏器联合摘取及动物实验的基础上，在临床施行ＳＰＫＴ３例，胰十二指肠移植于右髂窝，肾脏移植于左髂窝，腹主动脉与肠系膜上动脉袖片与髂外动脉端－侧吻合，门静脉与髂外静脉端－侧吻合，胰腺外分泌引流采用经膀胱途径。结果：１例已存活８个月，术后未用胰岛素，胰肾功能良好，无并发症，已恢复正常生活和工作；１例术后４７天死于脑出血，死亡时胰肾功能良好；１例术后４９天胰腺动脉血栓形成，死于坏死性胰腺炎。结论：ＳＰＫＴ是治疗糖尿病并发终末期肾病的一种切实可行的有效方法，它将成为治疗该病的一种安全、有效、常规治疗方法。
Objective: To explore the feasible method of pancreas-kidney transplantation (SPKT) in our country and apply it in clinic. Methods: On the basis of more than 80 celiac and multiple organ extraction from cadaver donors and animal experiments, 3 cases of SPKT were treated clinically and the pancreatic duodenum was transplanted into the right iliac fossa. The kidneys were transplanted into the left iliac fossa and abdominal aorta And the superior mesenteric artery sleeve and the external iliac artery end-side anastomosis, portal vein and external iliac vein end-side anastomosis, pancreatic excretory drainage by the bladder route. One patient had died of cerebral hemorrhage 47 days after operation, and the function of pancreas and kidney was good at the time of death. One patient died of cerebral hemorrhage after operation, One case had pancreatic arterial thrombosis 49 days after operation and died of necrotizing pancreatitis. Conclusion: SPKT is a feasible and effective method for the treatment of diabetic end-stage renal disease. It will become a safe, effective and routine treatment for the disease.