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目的 :探讨卵巢平滑肌肿瘤的临床和病理学特点、组织学来源和治疗方法。方法 :对作者所在医院近 4年收治的 5例卵巢平滑肌肿瘤 (平滑肌瘤 3例 ,平滑肌肉瘤 2例 )的临床和病理资料进行回顾性分析。结果 :卵巢平滑肌肿瘤的临床表现类似于其他卵巢肿瘤 ,无特异性症状和体征。卵巢平滑肌瘤可以产生腹水 ,其机制可能同卵巢纤维瘤。卵巢平滑肌肿瘤的组织学来源 :绝经前的部分病例可能来源于子宫内膜异位症 ,另一部分病例和绝经后的病例则可能来源于卵巢间质或卵巢门的血管壁平滑肌。卵巢平滑肌肿瘤的治疗以手术治疗为主 ,恶性者术后辅以腹腔和全身化疗。结论 :卵巢平滑肌肿瘤的组织学来源不是单一的。要探索卵巢平滑肌肉瘤的最佳治疗方案 ,尚需积累较多病例。
Objective: To investigate the clinical and pathological characteristics of ovarian smooth muscle tumors, histological sources and treatment methods. Methods: The clinical and pathological data of 5 cases of ovarian smooth muscle tumors (3 cases of leiomyoma and 2 cases of leiomyosarcoma) admitted to the hospital of the author were retrospectively analyzed. Results: The clinical manifestations of ovarian smooth muscle tumors resemble other ovarian tumors with no specific signs and symptoms. Ovarian leiomyoma can produce ascites, its mechanism may be the same ovarian fibroids. Histology of Ovarian Smooth Muscle Tumors: Some cases of premenopausal women may originate from endometriosis, and the other cases and postmenopausal cases may originate from the vascular wall smooth muscle of ovarian stroma or ovary. Surgical treatment of ovarian smooth muscle tumor-based, malignant were supplemented with intraperitoneal and systemic chemotherapy. Conclusion: The histological origin of ovarian smooth muscle tumors is not single. To explore the best treatment of ovarian leiomyosarcoma, the need to accumulate more cases.