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本文报道4例膝关节球孢子菌性滑膜炎,其中2例在出现膝关节的症状前,经痰培养及皮肤组织活检证实有肺部及面、躯干部皮肤的球孢子菌感染,另2例为原发性,在明确诊断前分别有关节症状16年与2年之久。临床症状:患部关节疼痛、关节肿胀、关节腔渗液、活动度受限、局部皮温不高,症状可呈间歇性。诊断:如患者有播散性球孢子菌病病史,当出现关节渗液时应立即想到滑膜感染的可能。但如病史阴性,亦无其他部位活动性病变,要作出早期诊断是有一定困难的;但实验室检查有助于本病的诊断,包括球孢子菌素皮试、血清补体结合试验及真菌培养。作者报道的4例球孢子菌素皮试全部阳性。补
This article reports four cases of coccoid synovitis of the knee, two cases of symptoms of the knee before the emergence of sputum culture and skin biopsy confirmed coccidioidomycosis of the lungs and facial, trunk skin, and the other 2 Cases of primary, prior to the diagnosis of a joint symptoms were 16 years and 2 years. Clinical symptoms: affected area joint pain, joint swelling, joint cavity effusion, limited mobility, local skin temperature is not high, the symptoms can be intermittent. Diagnosis: If the patient has a history of disseminated coccidioidomycosis, synovial infection should be immediately thought of when there is an effusion of the joint. However, if history is negative and there are no other active lesions, it is difficult to make early diagnosis. However, laboratory tests are helpful for the diagnosis of the disease, including coccidiosis skin test, serum complement fixation test and fungal culture . The authors reported 4 cases of coccidioid skin test all positive. Make up