先锋必系头孢菌素抗生素,过敏反应发生率虽然低,但仍应引起注意。我院发生2例先锋必所致严重过敏反应,现报道如下。例1 男,5 1/2岁,住院号16394。因发热咳嗽1天经当地医院治疗无效入院。体检:T38.3℃,血压12/8KPa,精神稍差,营养发育正常,呼吸28次/分,口唇无紫绀。两肺中等量细湿罗音,心脏无杂音。肝脾未触及。神经系统无异常。白细胞18.9×10~9/L, Pioneer will cephalosporin antibiotics, although the incidence of allergic reactions, but it should be noted. 2 cases occurred in our hospital will lead to serious allergic reactions, are reported below. Example 1 Male, 5 1/2 years old, hospital number 16394. 1 day due to fever cough hospital treatment invalid admission. Physical examination: T38.3 ℃, blood pressure 12 / 8KPa, less healthy, normal nutrition, breathing 28 beats / min, no cyanosis of lips. Middle lungs moderate wet rales, no noise in the heart. Liver and spleen not touched. Nervous system no abnormalities. WBC 18.9 × 10 ~ 9 / L,