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目的:通过对郎格罕细胞组织细胞增生症特殊型的分析,提高对该症的认识,减少其漏诊及误诊率。方法:回顾性调查分析21例首发症状特殊的LCH患者。结果:21例起病特殊的患者中,反复发热5例,黄疸4例,面色苍黄3例,发热、咳嗽3例,颜面部水肿伴肿块2例,反复腹泻、反复外耳道流脓、胸腰部疼痛及便血分别1例。结论:LCH临床表现多样,应警惕某些以特殊临床症状为首发症状者,尽量减少其误诊或漏诊。
OBJECTIVE: To improve the understanding of this disease and reduce its missed diagnosis and misdiagnosis rate by analyzing the special type of Langerhans cell histiocytosis. Methods: A retrospective analysis of 21 cases of first-episode LCH patients. Results: In 21 patients with special onset, there were 5 cases of recurrent fever, 4 cases of jaundice, 3 cases of pale yellowness, 3 cases of fever and cough, 3 cases of facial edema with mass, recurrent diarrhea, repeated external auditory canal abscess, thoracolumbar pain And one case of hematochezia respectively. Conclusion: The clinical manifestation of LCH is varied, we should be wary of some patients with special clinical symptoms as the first symptom, to minimize their misdiagnosis or missed diagnosis.