Ⅷ因子(FⅧ)系一糖蛋白,分子最为0.6～20×10~6dalton。目前已知 F Ⅷ复合体的独立功能有三:即具有FⅧ凝血剂(Ⅷ:C),FⅧ相关抗原(ⅧR:AG)和FⅧ瑞斯托霉素辅因子活性(Ⅷ:Rcof)。FⅧ有关物质可在血浆血小板和血管内皮中测出。FⅧ活性异常可出现于各种疾病。在严重肾脏病FⅧ水平增加,并与肾脏损害的严重性有关,特别在预后不良的急性肾小球肾炎。本文研究了各类慢性肾 Factor Ⅷ (F Ⅷ) is a glycoprotein, the molecule most 0.6 ~ 20 × 10 ~ 6dalton. It has been known that there are three independent functions of F Ⅷ complex: FⅧ coagulation agent (Ⅷ: C), FⅧ-related antigen (Ⅷ R: AG) and FⅧ ristocetin cofactor activity (Ⅷ: Rcof). F Ⅷ related substances can be detected in plasma platelets and vascular endothelium. FⅧ abnormal activity can occur in a variety of diseases. In severe renal disease increased levels of F Ⅷ, and the severity of renal damage, especially in the poor prognosis of acute glomerulonephritis. This article studies various types of chronic kidney disease