研究了一种单环 β 内酰胺抗生素在酸性和碱性情况下的反应机理 ;通过比较反应活化能 ,研究结果表明 :在碱性情况下 ,无论是开环还是闭环反应相对而言都容易发生反应 ,同时在反应过程中有电子迁移现象 . The reaction mechanism of a single-ring β-lactam antibiotic in acidic and basic conditions was investigated. By comparing the activation energy, the results show that in the alkaline condition, both the ring-opening and the ring-closure reactions are relatively easy Reaction, at the same time in the reaction process of electron transfer phenomenon.