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自从Abelev(1963)Tartarinor(1964)先后证明肝癌小鼠及病人血清中存在甲胎蛋白(AFP)以来,从此AFP的研究广泛开展。应用AFP进行大规模原发性肝癌高危人群的普查,已成为早期检测原发性肝细胞癌的重要手段,在良性肝病中也有其重要意义。随着检测技术的不断改进,又被引进产科某些疾患的预报和筛查。本文就AFP检测的临床意义浅述如下:
AFP studies have been extensive since Abelev (1963) Tartarinor (1964) has demonstrated the presence of AFP in sera from both liver cancer and human patients. The application of AFP for the screening of high-risk patients with large-scale primary liver cancer has become an important measure for detecting primary hepatocellular carcinoma in the early stage and also has an important role in benign liver disease. With the continuous improvement of testing technology, it has also been introduced into the forecast and screening of certain diseases in obstetrics. This article on the clinical significance of AFP detection as follows: