热休克蛋白(HSP)是一组在进化过程中高度保守的蛋白质大家族,普遍存在于细菌乃至人类体内。大多数HSP是细胞的结构蛋白,只有部分HSP可因应激而生成或生成增加。高温、缺氧、感染、创伤、中毒等应激原都可诱导HSP生成,因此HSP又称应激蛋白。近年研究发现HSP与胃部疾病关系密切, Heat shock proteins (HSPs) are a family of proteins that are highly conserved during evolution and are ubiquitous in bacteria and even in humans. Most HSPs are structural proteins of cells, and only part of HSPs can be generated or increased due to stress. High temperature, hypoxia, infection, trauma, poisoning and other stressors can induce HSP formation, so HSP is also called stress protein. In recent years, studies have found that HSP and gastric diseases are closely related,