本文采用~(125)I释放法检测小鼠和人的体外天然杀伤细胞(NK)活性,用~(125)I清除法检测小鼠体内NK活性,同时以Lewis 肺癌细胞对小鼠进行肺瘤克隆形成试验,研究了冬虫夏草醇提液(CS-Ⅱ)对小鼠和人NK活性及小鼠肺瘤克隆形成的影响。实验表明,CS-Ⅱ对小鼠和人的NK活性具有增强作用,并能保护免疫抑制小鼠NK活性的降低,抑制小鼠肺瘤克隆的形成。 In this study, ~(125)I release method was used to detect the natural killer (NK) activity of mice and humans. The NK activity in mice was detected by the ~(125)I clearance method, and the lung tumors of mice were performed with Lewis lung cancer cells. A cloning formation assay was conducted to study the effects of the extract of Cordyceps sinensis (CS-II) on the activity of mouse and human NK cells and the formation of lung tumor clones in mice. Experiments show that CS-II can enhance the NK activity in mice and humans, and can protect the immunosuppressive mice NK activity and inhibit the formation of mouse lung tumor clones.