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阿朴列辛——1-肼基酞嗪盐酸盐,作为降压药。作者从最易得到的原料酞酮(Ⅰ)开始,合成1氯酞嗪(Ⅱ),然后以肼基代氯而得(Ⅲ),反应如下:
Apolesin - 1-hydrazinophthalazine hydrochloride, as a antihypertensive drug. Starting from the most readily available starting phthalidone (I), the synthesis of 1 chlorophthalazine (II) followed by hydrazine (III) chloride gave the following reaction: