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目的:研究继发性甲状旁腺功能亢进症行甲状旁腺切除术的临床效果。方法:病例来源:我院住院接受治疗的83例尿毒症继发性甲状旁腺功能亢进症患者。观察指标:(1)手术成功率、术后1周疼痛缓解率;(2)6个月复发率;(3)治疗前和治疗后患者血磷、血钙、碱性磷酸酶、血清全段甲状旁腺素的差异。结果:(1)术b组、术a组手术成功率、术后1周疼痛缓解率相似,X~2统计处理无显著差异,P>0.05;(2)术b组相比于术a组6个月复发率更低,X~2统计处理有显著差异,P<0.05;(3)治疗前两组血磷、血钙、碱性磷酸酶、血清全段甲状旁腺素相似,t统计处理无显著差异,P>0.05;治疗后两组患者血磷、血钙、碱性磷酸酶、血清全段甲状旁腺素均降低,t统计处理有显著差异,P<0.05,但组间P>0.05。结论:继发性甲状旁腺功能亢进症行甲状旁腺切除术的临床效果确切,其中,甲状旁腺次全切更有助于预防复发。
Objective: To study the clinical effect of parathyroidectomy in patients with secondary hyperparathyroidism. Methods: Case Source: 83 hospitalized patients with uremia secondary hyperparathyroidism treated in our hospital. (2) 6-month recurrence rate; (3) Before treatment and after treatment, patients with serum phosphorus, serum calcium, alkaline phosphatase, whole serum Parathyroid hormone differences. Results: (1) The success rate of surgery in group b and group A was similar to that in group A at one week after operation, and there was no significant difference in X ~ 2 statistics (P> 0.05). (2) Compared with group A 6 months, the recurrence rate was lower, X ~ 2 statistical significant difference, P <0.05; (3) before treatment, serum phosphorus, serum calcium, alkaline phosphatase, serum parathyroid hormone similar, t statistics P <0.05; after treatment, the serum phosphorus, serum calcium, alkaline phosphatase and parathyroid hormone in serum of the two groups were decreased, there was a significant difference between the two groups (P <0.05), but P > 0.05. Conclusions: The clinical effect of parathyroidectomy in patients with secondary hyperparathyroidism is exact, in which subtotal parathyroidectomy is more helpful to prevent recurrence.