由职业卫生国际协会及其常设委员会主办、工作场所空气中潜在毒物容许浓度科学委员会组织的苯毒理学国际专题讨论会于1976年11月9～11日在巴黎召开。参加会议的有来自16个国家的49位代表与ILO和WHO的代表。会议讨论了与接触苯有关的实验毒理学和流行病学方面所得到的资料,侧重于工人的剂量-反应关系,特别是接触低浓度的远期作用。内容如下。[苯的生产和应用] 苯的生产日益增加,带来接触的危险,应采取措施使加工,运输和保管人员的按触减至最少。[苯的代谢、分布和排泄] 无论给药途经如何,尿中苯的代谢物均相同。多数研究表明,在人和动物 The International Symposium on Benzene Toxicology organized by the Scientific Committee on Hosted Organisms of Occupational Health and its Standing Committee on the Allowable Concentration of Potentially Toxic Substances in the Air of Workplaces was held in Paris from November 9 to November 1976. 49 delegates from 16 countries and ILO and WHO representatives attended the conference. The meeting discussed data obtained from experimental toxicology and epidemiology related to benzene exposure, focusing on the dose-response relationship of workers, especially the long-term effects of exposure to low concentrations. The content is as follows. [Production and Application of Benzene] The production of benzene is increasing and exposing to the danger of exposure, and measures should be taken to minimize the amount of exposure by the processing, transport and storage personnel. [Benzene metabolism, distribution and excretion] Regardless of the route of administration, the metabolites of benzene in urine are the same. Most studies show that in humans and animals