摘要目的使用功能MRI探讨伴中央颞区棘波良性癫癎日间期日样放电(IED)发生时的功能连接组学改变。材料与方法本前瞻性研究得到当地机构伦理委员会批准并遵循HIPAA。连续招募参与者并签订知情同意书。根据脑电同步3.0 T静息态MRI记录的数据,将43例右利手病人分为20例IED组[女13例,男7例;平均年龄(9.00±1.95)岁]和23例非IED组[女11例,男12例;平均年龄(10.22±2.13)岁]。采用单因素方差分析法比较病人组与对照组的功能连接组学特征(图论分析评估)的差异。28例对照组[右利手,女13名,男 Abstract Objective To explore the functional histopathological changes during the daytime type IED with central temporal area benign epilepsy by functional MRI. Materials and Methods This prospective study was approved by a local ethics committee and followed HIPAA. Continuous recruitment of participants and signed informed consent. According to the data of resting electro-magnetic resonance 3.0T MRI, 43 right-handed patients were divided into 20 cases of IED (13 female, 7 male; mean age 9.00 ± 1.95 years) and 23 non-IED Group [female 11, male 12; mean age (10.22 ± 2.13) years]. One-way analysis of variance was used to compare differences in functional histomorphology (graph theory analysis) between the patient group and the control group. 28 cases of control group [right hand, female 13, male