肠道病毒系细小RNA病毒科中的一个亚属,包括引起人类广泛疾病的一大群病原。肠道病毒血清型的鉴定十分重要,因其在流行病学、临床疾病与病毒的血清型别之间存在密切的关系。实验诊断肠道病毒感染主要依靠病毒在易感细胞中的增殖,并用中和试验方法鉴别感染病毒的血清型别。为了便于鉴别,常采用两组交叉混合的抗血清进行中和病毒的试 Enterobacteriaceae is a subgenus of the genus Picornaviridae that includes a large group of pathogens that cause a wide range of human diseases. Identification of serogroups of enteroviruses is important because of the close relationship between epidemiology, clinical disease and serotypes of the virus. Experimental diagnosis of enterovirus infections rely mainly on the proliferation of the virus in susceptible cells and identification of serotypes of the infected virus by neutralization assays. For ease of identification, two sets of cross-mixed antisera are often used to neutralize the virus