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目的:运用3D打印技术建立具有精准解剖结构的先天性心脏病三维模型。探讨3D打印的心脏模型对于临床诊断和手术计划制定的意义。材料与方法:一例4个月的儿童经超声心动图诊断患有复杂先天性心脏病,行64排前门控增强CT扫描后获得图像资料;通过MIMICS 17.0软件将CT DICOM数据导入并对感兴趣区域(ROI)做图像后重建处理;使用区域生长的方法根据CT值的不同来分割图像之后生成标准镶嵌语言(Standard Tessellation Language,STL)文件数据;将数据导入OBJET 260 3D打印机后即完成建模过程。结果:3D模型不但能清晰地显示上述解剖畸形,且能更好地展示室间隔缺损位置、室间隔缺损与房室瓣及两大血管的关系、两大血管的空间结构关系及主动脉缩窄的立体展现。结论:3D打印技术应用于先天性心脏病,不但能清晰显示解剖畸形,还能更好地显示心内畸形和心外大血管的空间关系,将更有效地辅助诊断并应用于术前手术方案的制定,为先天性心脏病患者带来精准化的治疗。
Objective: To establish a three-dimensional model of congenital heart disease with accurate anatomy using 3D printing technology. To explore the significance of 3D printed heart model for clinical diagnosis and surgical planning. MATERIALS AND METHODS: A 4-month-old child with complex congenital heart disease diagnosed by echocardiography was scanned with a 64-row front-gate enhanced CT scan to obtain the image data. The CT DICOM data was imported by MIMICS 17.0 software and analyzed for the region of interest (ROI) to reconstruct the image; using the method of region growing to generate Standard Tessellation Language (STL) file data after dividing the image according to the CT value; and importing the data into the OBJET 260 3D printer to complete the modeling process . Results: The 3D model can not only clearly show the above-mentioned anatomic deformity, but also better display the location of ventricular septal defect, the relationship between ventricular septal defect and atrioventricular valve and two major vessels, the spatial structure of two major vessels and the aortic constriction Three-dimensional show. Conclusion: 3D printing technology applied to congenital heart disease not only can clearly show the anatomic deformity, but also can better display the spatial relationship between intracardiac malformation and extracardiac macrovascular, and it will be more effective in diagnosing and applying in preoperative surgical plan The development of accurate congenital heart disease treatment.