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探讨了小柴胡汤对肿瘤坏死因子的诱导作用,结果表明,小柴胡汤能剂量依赖性地诱导外周血单核细胞产生肿瘤坏死因子,小柴胡汤的类方大柴胡汤和柴胡桂枝汤也有同样的作用。而对照药小青龙汤则变化轻微,否定了小柴胡汤的体外作用为非特异性的结论。认为小柴胡汤预防致癌作用的重要因素,是其具有诱导肿瘤坏死因子的作用。
The inducing effect of Xiao Chai Hu Tang on tumor necrosis factor was investigated. The results showed that Xiao Chai Hu Tang could induce tumor necrosis factor in peripheral blood mononuclear cells in a dose-dependent manner, and Xiao Chai Hu Tang and Chai Hu Gui Zhi Tang in Xiao Chai Hu Tang also had the same effect. The role. However, the control Xiaoqinglong Decoction was slightly changed, negating the conclusion that Xiaochaihu Decoction was non-specific in vitro. It is believed that Xiaochaihu Decoction has an important role in the prevention of carcinogenesis because it has the effect of inducing tumor necrosis factor.