以化学药物预防和治疗胃癌淋巴结转移可改善患者的预后和生存质量.胃癌淋巴化疗能通过三种方法提高疗效:①胃镜下胃粘膜内、癌灶内注药、术前或术中胃周动脉给药、术中由浆膜胃壁内注药;②使用抗癌药的乳剂型;③日本研制的丝裂霉素C-右旋糖苷已应用于临床,其淋巴组织浓度为乳剂的50倍,抗肿瘤疗效显著,副作用轻微. The use of chemical drugs to prevent and treat lymph node metastasis in gastric cancer can improve the prognosis and quality of life of patients. Lymph node chemotherapy for gastric cancer can improve efficacy through three methods: 1 Gastric mucosal injection in gastric mucosa, intracarotid injection, preoperative or intraoperative gastrointestinal artery Drug administration, intraoperative injection of drug by serosal stomach wall; 2 use of emulsion type of anticancer drug; 3 mitomycin C-dextran developed in Japan has been used clinically, and its lymph tissue concentration is 50 times that of emulsion. Significant anti-tumor efficacy, mild side effects.