爆发鱼病是妨碍养殖渔业高产的主要因素之一,养殖过程即是鱼病防治过程。鱼病工作应抓“预防为主、无病先防”的原则,经过多年生产实践已为人们广泛认识和采用。但在长期使用各种药物防治过程中,业已发现鱼类生物病原具有抗药性。相对而言,预防病原体抗药性的产生还远未受到重视。1 抗药性的危害和后果鱼类病原体抗药性一旦形成或加强,因为新要求的药量增大,会提高养鱼成本,降低经济效益;某些药物在鱼体各组织、器官残留量增大,影响鱼的摄食、生长,经常使用,由于在鱼体内的蓄积,还能改变鱼的肉质肉味,进 The outbreak of fish diseases is one of the main factors that hinder the high yield of aquaculture fisheries. The breeding process is the fish disease prevention and control process. The work of fish diseases should pay attention to the principle of “prevention first and disease prevention first”. After years of production practice, it has been widely recognized and adopted by people. However, in the long-term use of various drug control processes, it has been found that fish biological pathogens are resistant. Relatively speaking, the prevention of the emergence of pathogen resistance is far from being taken seriously. 1 the harm and consequences of drug resistance Once the formation or strengthening of fish pathogen resistance, because the new requirements of the drug increases, will raise fish costs and reduce economic benefits; some drugs in fish tissues and organs increased , Affect the fish’s feeding, growth, regular use, due to the accumulation of fish in the body, but also to change the flesh meat flavor, into