论文部分内容阅读
目的探讨起搏器不同起搏模式对病态窦房结综合征患者中医证候的影响及其血流动力学机制。方法75例病态窦房结综合征患者在起搏器植入术前及术后1个月进行证候症状积分及血流动力学指标检查,比较不同起搏模式间证候症状积分及血流动力学指标的差异性。结果起搏器植入术后中医证候症状积分均低于手术前(P<0.05)。AAI起搏及DDD起搏对左室射血分数(LVEF)、每搏射血量(SV)、心排血量(CO)、心排血指数(CI)、左室舒张末容积(LVEDV)的改善与VVI起搏比较差异有统计学意义(P<0.05),AAI起搏对CO、CI及LVEDV的改善与DDD起搏相比差异有统计学意义(P<0.05)。结论起搏器植入可改善病态窦房结综合征患者血流动力学及中医证候,而不同的起搏模式中,AAI起搏优于DDD起搏优于,VVI起搏,提示起搏治疗可通过血流动力学因素中CO、CI、LVEDV从而影响病态窦房结综合征的中医证候。
Objective To investigate the effects of pacemaker pacing modes on TCM syndromes in patients with sick sinus syndrome and its hemodynamic mechanism. Methods Seventy-five patients with sick sinus syndrome were examined with symptom scores and hemodynamics before and one month after implantation of pacemaker, and the systolic symptom score and blood flow were compared between different pacing modes The difference of kinetic indexes. Results The scores of TCM syndromes after pacemaker implantation were lower than those before operation (P <0.05). The effects of AAI pacing and DDD pacing on left ventricular ejection fraction (LVEF), stroke volume (SV), cardiac output (CO), cardiac output index (CI), left ventricular end diastolic volume (LVEDV) (P <0.05). The improvement of CO, CI and LVEDV in AAI pacing was significantly different from DDD pacing (P <0.05). Conclusion Pacemaker implantation can improve hemodynamics and TCM syndromes in patients with sick sinus syndrome. However, in different pacing modes, AAI pacing is superior to DDD pacing and VVI pacing, suggesting that pacing Treatment through the hemodynamic factors CO, CI, LVEDV affect the symptoms of sick sinus syndrome.