Management of renal replacement therapy among adults in French intensive care units: A bedside pract

来源 :重症医学(英文) | 被引量 : 0次 | 上传用户:
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Background:

This study aimed to investigate renal replacement therapy (RRT) practices in a representative nationwide sample of French intensive care units (ICUs).

Methods:

From July 1 to October 5 2021, 67 French ICUs provided data regarding their ICU and RRT implementation. We used an online questionnaire to record general data about each participating ICU, including the type of hospital, number of beds, staff ratios, and RRT implementation. Each center then prospectively recorded RRT parameters from 5 consecutive acute kidney injury (AKI) patients, namely the indication, type of dialysis catheter used, type of catheter lock used, type of RRT (continuous or intermittent), the RRT parameters initially prescribed (dose, blood flow, and duration), and the anticoagulant agent used for the circuit.

Results:

A total of 303 patients from 67 ICUs were analyzed. Main indications for RRT were oligo-anuria (57.4%), metabolic acidosis (52.1%), and increased plasma urea levels (47.9%). The commonest insertion site was the right internal jugular (45.2%). In 71.0% of cases, the dialysis catheter was inserted by a resident. Ultrasound guidance was used in 97.0% and isovolumic connection in 90.1%. Citrate, unfractionated heparin, and saline were used as catheter locks in 46.9%, 24.1%, and 21.1% of cases, respectively.

Conclusions:

Practices in French ICUs are largely compliant with current national guidelines and international literature. The findings should be interpreted in light of the limitations inherent to this type of study.

其他文献
Cardiogenicshock(CS)isaleadingcauseofmortalityworldwide.CSpresentationandmanagementinthecurrenterahavebeenwidelydepictedinepidemiologicalstudies.Itstreatmentiscodifiedandreliesonmedicalcareandextracorporeallifesupport(ECLS)inthebridgetorecovery,chronicmec
Resuscitationofsepticshockisacomplexissuebecausethecardiovasculardisturbancesthatcharacterizesepticshockvaryfromonepatienttoanotherandcanalsochangeovertimeinthesamepatient.Therefore,differenttherapies(fluids,vasopressors,andinotropes)shouldbeindividuallya
Theapoptosisrepressorwithcaspaserecruitmentdomain(ARC)playsacriticalroleinextrinsicapoptosisinitiationviadeathreceptorligands,physiologicalstress,infectionresponseinatissue-dependentmanner,endoplasmicreticulum(ER)stress,genotoxicdrugs,ionizingradiation,ox
Leftventricularassistdevice(LVAD)therapyiswell-establishedinthetreatmentofend-stagecardiacfailure.Indicationsarebridgetotransplant(BTT),bridgetocandidacy(BTC),bridgetorecovery(BTR),anddestinationtherapy(DT).Thedurabilityandadverseevent(AE)rateofLVADshavei
Cardiogenicshock(CS)isacomplexclinicalsyndromewithahighmortalityrate.Itcanoccurtoduetomultipleetiologiesofcardiovasculardiseaseandisphenotypicallyheterogeneous.Acutemyocardialinfarction-relatedCS(AMI-CS)hashistoricallybeenthemostprevalentcause,andthus,res
Cardiogenicshock(CS)isalife-threateningconditioncharacterizedbyacuteend-organhypoperfusionduetoinadequatecardiacoutputthatcanresultinmultiorganfailure,whichmayleadtodeath.ThediminishedcardiacoutputinCSleadstosystemichypoperfusionandmaladaptivecyclesofisch
Microvascularalterationswerefirstdescribedincriticallyillpatientsabout20yearsago.Thesealterationsarecharacterizedbyadecreaseinvasculardensityandpresenceofnon-perfusedcapillariesclosetowell-perfusedvessels.Inaddition,heterogeneityinmicrovascularperfusionis
Background:HeartdiseaseistheleadingcauseofdeathintheUnitedStates.Thelengthofstay(LOS)isawell-establishedparameterusedtoevaluatehealthoutcomesamongcriticallyillpatientswithheartdiseaseincardiacintensivecareunits(CICUs).Whileevidencesuggeststhatthepresenceo
Background:Whilecentralvenouspressure(CVP)measurementisusedtoguidefluidmanagementforhigh-risksurgicalpatientsduringtheperioperativeperiod,itsrelationshiptopatientprognosisisunknown.Methods:Thissingle-center,retrospectiveobservationalstudyenrolledpatientsu