为探讨一种能在较短时间内灭活ＨＢＶ的消毒方法，用不同浓度的戊二醛消毒剂，擦拭消毒已污染ＨＢｓＡｇ阳性血清的口腔常用诊疗器械，用ＥＬＩＳＡ法检测ＨＢｓＡｇ。用２％～３％的戊二醛消毒剂，擦拭消毒一遍已污染ＨＢｓＡｇ的口腔器械，ＨＢｓＡｇ的灭活率为１６．１％，采用擦拭三遍消毒的方法，ＨＢｓＡｇ的灭活率为９９％～１００％。提示，选用较高浓度的戊二醛消毒剂，擦拭消毒污染的口腔器械，可达到灭活ＨＢｓＡｇ的目的 To explore a disinfection method that can inactivate HBV in a short period of time, different concentrations of glutaraldehyde disinfectant were used to wipe out the commonly used oral diagnostic instruments for disinfection of contaminated HBsAg-positive sera and to detect HBsAg by ELISA. With 2% ~ 3% glutaraldehyde disinfectant, wipe once again contaminated HBsAg oral instruments, HBsAg inactivation rate was 16.1%, using wipe three times disinfection method, the inactivation rate of HBsAg was 99% ~ 100%. Tip, choose a higher concentration of glutaraldehyde disinfectant, wipe disinfection of contaminated oral instruments, can achieve the purpose of inactivation of HBsAg