多原发癌临床上少见,以往报道中多为双原发及三原发癌,四原发癌极罕见。我院1954～1992年共收治多原发癌500例,四原发癌仅2例占0.4％,现将四原发癌2例报告如下。病例摘要例1:女性,52岁。初诊,右乳腺癌,行右乳癌根治术。术后5年,又患左乳髓样癌,手术后再4年,以腹腔肿瘤住院,检查为双侧卵巢肿瘤,手术双侧卵巢切除。 Many primary cancers are clinically rare. In previous reports, they were mostly bi-primary and tri-primary cancers. The four primary cancers were extremely rare. In our hospital from 1954 to 1992, a total of 500 cases of multiple primary cancers were treated, and only two cases of four primary cancers accounted for 0.4%. Two cases of four primary cancers are now reported as follows. Case summary Example 1: Female, 52 years old. Newly diagnosed, right breast cancer, right radical mastectomy. Five years after surgery, she suffered from left medullary carcinoma and four years after surgery. She was hospitalized with an abdominal cavity tumor and checked for bilateral ovarian tumors. She had bilateral ovariectomy.