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目的:观察头孢羟氯苄三联疗法根除幽门螺杆菌(Hp)的临床应用价值.方法:对30例Hp阳性的十二指肠球都溃疡病人用头孢羟氨苄、奥美拉唑、甲硝唑三联疗法治疗2周并与25例行阿莫西林、奥美拉唑、甲硝唑三联疗法的病人进行对照.结果:治疗组与对照组停药4周后Hp根除率分别为83％(25/30)及84％(21/25)(P＞0.05),溃疡愈合率分别为:90/(27/30)及92％(23/25)(P＞0.05).治疗组不良反应少.Hp对头孢羟氨苄的敏感率达90％.结论:以头孢羟氨苄为中心的三联疗法能有效的根除Hp,不良反应少,值得进一步尝试.“,”Objeclive:To observe the value of cefadroxil triple therapy for the eradication of Helicobacter py-lori (Hp). Methods:30 cases with Hp positive duodenal ulcer were treated with triple therapy of cefadroxil, omepra-zole, metronidazole for 2 weeks. 25 cases treated with amoxycillin triple-therapy (amoxycillin replace cefadroxil) se-tered as the control.Results:The results showed that the rates of ulcer healing and Hp eradication in cefadroxilgroup were 90% (27/30) and 83% (25/30), respectively compared to 92% (25/30) and 84 % (21/25 ) in the controlgroup. However, rilte of adverse reactions was significantly lower in the treatment group. Conclusion:Cefadroxiltriple therapy is a choice of clinical practice for the eradication of Hp.