多发性硬化症(MS)是一种中枢神经系统自身免疫性炎症脱髓鞘疾病。改善病情治疗(DMTs)是目前常用于缓解期的治疗方法,受个体化差异、疾病所处阶段、给药时机等因素影响,其治疗效果存在差异。本研究对DMTs的起始时机、治疗计划的改变和停药等问题进行综述,旨在为MS的治疗提供参考依据。 Multiple sclerosis (MS) is a central nervous system autoimmune demyelinating disease. Improving the treatment of disease (DMTs) is currently used in remission of treatment, subject to individual differences, the stage of the disease, the timing of administration and other factors, the treatment effect is different. This study summarizes the initial timing of DMTs, changes in treatment plans, and discontinuation of DMTs in order to provide a reference for the treatment of MS.