,The crystal structure of Zika virus helicase: basis for antiviral drug design

来源 :蛋白质与细胞 | 被引量 : 0次 | 上传用户:al035258
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Dear Editor The genus of Flavivirus contains important human pathogens,including dengue (DENV),yellow fever (YFV),West Nile (WNV),Japanese encephalitis (JEV),and tick-boe encephalitis (TBEV) viruses,which cause a number of serious human diseases throughout the world (Pierson TC,2013).Zika virus (ZIKV) is also an arthropod-boe flavivirus,which was initially isolated in 1947 from a febrile sentinel rhesus monkey in the Zika forest in Entebbe,Uganda.
其他文献
Dear Editor,Influenza is a contagious,acute respiratory disease caused by influenza viruses.Type A influenza virus has a broad host range and has caused substan
期刊
Dear Editor,Accurate measurement of distances within and between biological macromolecules is important for structure-function studies,for investigating conform
期刊
Dear Editor,hCLP46 (human CAP10-like protein 46 kDa) was initially isolated and identified from human acute myeloid leukemia transformed from myelodysplastic sy
期刊
Dear Editor,Polycomb repressive complex 2 (PRC2) plays a critical role in organ development,adult homeostasis,and tumorigenesis via enzymatic activities to di-o
期刊
Dear Editor,The prevalence of multidrug-resistant Mycobacterium tuberculosis (M.tuberculosis) is an increasing problem worldwide (Zumla et al.,2013;Dong et al.,
期刊
近日,佳品网与美国零售巨头梅西百货的合作有了实质性进展。据悉,佳品网将在米岚城市奥莱开发的奥特莱斯内开设首个佳品网实体店,该店所有货源均由美国梅西百货提供。据佳品
Dear Editor,The methylation modifications of histone 3 lysine 4 (H3K4) have essential effects on biological processes including gene expression and transcriptio
期刊
Dear Editor,RND (resistance nodulation-cell division) exporters are widely expressed across the lineage of Gram-negative bacteria (Fig.S1).Their functional role
期刊
Dear Editor,Klebsiella pneumoniae (KP) is an important opportunistic pathogen causing community-acquired and nosocomial infections.When the host is immunocompro
期刊
Dear Editor,P-Rex1 is a Rac-selective guanine nucleotide exchange factor (GEF) that is synergistically activated by G-protein coupled receptors and receptor tyr
期刊