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目的估算99m Tc-甲氧基异丁基异腈(MIBI)心肌灌注显像患者对公众人群及核医学技师的照射剂量(RD)。方法前瞻性选取2015年1月-6月行99m Tc-MIBI心肌灌注显像的55例患者,其中男30例,女25例;年龄25~87岁,平均(63.6±15.1)岁。在静脉注射99m Tc-MIBI 1.5 h后,利用辐射监测剂量仪测量患者0.3、1.0 m处的剂量当量率。依据国际辐射防护委员会提出的99m Tc-MIBI人体代谢速率及美国国家辐射防护和测量委员会提出的人类社会活动模式,计算99m Tc-MIBI心肌显像患者完成显像离开核医学科室后,对公众人群的RD。假定核医学技师因摆放体位短期接触99m Tc-MIBI心肌显像患者的时间为5 min,距离为0.3 m,计算技师的RD。结果与99m Tc-MIBI心肌显像患者夜间同床共睡的家庭成员RD为42.88~160.55μSv;白天接触的家庭成员,RD为7.50~29.38μSv;单位工作同事的RD为9.89~38.78μSv;邻座乘客的RD为124.48~466.06μSv。核医学技师每接触1位99m Tc-MIBI心肌显像患者,RD为1.72~6.44μSv。结论 99m Tc-MIBI心肌灌注显像患者对公众及核医学技师的RD远低于相应人群的照射剂量限值。
Objective To estimate the exposure dose (RD) of 99m Tc-methoxyisobutylisonitrile (MIBI) myocardial perfusion imaging to the public and nuclear medicine technicians. Methods Fifty-five patients with 99m Tc-MIBI myocardial perfusion imaging were selected prospectively from January 2015 to June 2015. There were 30 males and 25 females, ranging in age from 25 to 87 years (mean, 63.6 ± 15.1 years). After intravenous injection of 99m Tc-MIBI for 1.5 h, the dose equivalent rate at 0.3 and 1.0 m was measured using a radiation monitoring dosimeter. According to the 99m Tc-MIBI human metabolic rate proposed by the International Commission on Radiological Protection and the pattern of human social activities proposed by the National Radiation Protection and Surveillance Commission, 99m Tc-MIBI myocardial imaging patients were enrolled in the study. RD. Assuming that the nuclear medical technician calculated the RD of the technician for a short duration of exposure to 99m Tc-MIBI myocardial imaging with a position of 5 min and a distance of 0.3 m, Results The RD of family members sleeping at night with bedtime 99m Tc-MIBI was 42.88 ~ 160.55μSv. The RD was 7.50-29.38μSv and the working colleague RD was 9.89 ~ 38.78μSv. Passengers RD is 124.48 ~ 466.06μSv. For every 1 99m Tc-MIBI myocardial imaging patient exposed to a nuclear medicine technician, RD was 1.72 to 6.44 μSv. Conclusion The RD of 99m Tc-MIBI myocardial perfusion imaging to public and nuclear medicine technicians is much lower than the corresponding dose limits for the corresponding population.