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目的研究前列腺患者术前中性粒细胞与淋巴细胞比值(NLR)测定的临床价值。方法选择暨南大学附属珠海医院2010年1月-2016年12月收治的前列腺癌患者86例为研究对象,按照NLR高低分为观察组和对照组。观察组30例NLR≥2.80,对照组56例NLR<2.80,比较两组患者的NLR与前列腺癌危险分级、肿瘤侵犯范围、血清PSA等之间的关系,并得出结论。结果观察组患者的前列腺癌危险分级、血清PSA值均显著高于对照组患者,差异具有统计学意义(P<0.05);观察组患者的肿瘤侵犯范围显著广于对照组患者,差异具有统计学意义(P<0.05)。结论术前外周静脉血NLR与前列腺癌的恶性程度呈正相关,NLR越高癌症危险越高,预后越差,前列腺癌患者术前NLR测定具有较高的临床价值。
Objective To study the clinical value of preoperative neutrophil to lymphocyte ratio (NLR) in patients with prostate cancer. Methods 86 cases of prostate cancer admitted to Zhuhai Hospital Affiliated to Jinan University from January 2010 to December 2016 were selected as study subjects and divided into observation group and control group according to the level of NLR. In the observation group, the NLR≥2.80 in 30 cases and 56 cases in control group with NLR <2.80. The relationship between NLR and the risk grade of prostate cancer, the extent of tumor invasion, serum PSA and so on were compared between the two groups and the conclusion was drawn. Results In the observation group, the risk grade of prostate cancer and serum PSA were significantly higher than those in the control group (P <0.05). The tumor invasion rate in the observation group was significantly wider than that in the control group, and the difference was statistically significant Significance (P <0.05). Conclusion Preoperative NLR is positively correlated with the degree of malignancy of prostate cancer. The higher the NLR, the higher the risk of cancer and the worse the prognosis. The preoperative NLR of prostate cancer patients has high clinical value.