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胰岛素依赖型糖尿病(IDDM)患者在发病早期肾脏体积增大,肾小球滤过率增高。尚未见非胰岛素依赖型糖尿病(NIDDM)患者这方面系统研究的报告。本文对北京协和医院内分泌科糖尿病专病门诊随诊的87名NIDDM患者(年龄40～70岁,男性35名,女性52名,病程1周～32年)测定肾脏体积,肾小球滤过率(内生肌酐清除率法)、糖化血红蛋白(HbA_1)和尿白蛋白排除率。并对本院24名职工(年龄40～65岁,男性11名,女性13名,口服75g葡萄糖耐量正常,心,肝、肾功能正常,身高体重正常)进行上述测定,作为正常对照。NIDDM患者的病情不一,有刚从糖耐量低减转变成临床糖尿
Insulin-dependent diabetes mellitus (IDDM) patients with early onset of renal volume increased glomerular filtration rate increased. No systematic study has been reported on patients with non-insulin-dependent diabetes mellitus (NIDDM). 87 NIDDM patients (aged 40-70 years, 35 males and 52 females, duration of 1 week to 32 years) were followed up for the diagnosis and treatment of diabetes mellitus in Department of Endocrinology of Peking Union Medical College Hospital. The renal volume, glomerular filtration rate (Endogenous creatinine clearance rate), glycosylated hemoglobin (HbA_1) and urinary albumin exclusion rate. And the hospital staff of 24 (age 40 to 65 years old, 11 males and 13 females, oral glucose tolerance was normal 75g, heart, liver, kidney function, normal height and weight) as the normal control. NIDDM patients in different conditions, just from the impaired glucose tolerance into clinical diabetes