恶性血液病的发生发展涉及正常基因的突变或缺失 ,癌基因的异常表达以及其他多个相关基因的协同作用。基因芯片是近年发展起来的一项前沿生物技术 ,基因芯片技术在恶性血液病研究中的应用有助于白血病、淋巴瘤等的分型更深入、更精确 ,对指导治疗和判断预后更有实用意义。 The occurrence and development of hematologic malignancies involve the mutation or deletion of normal genes, the abnormal expression of oncogenes and the synergy of other related genes. Gene chip is a cutting-edge biotechnology developed in recent years, gene chip technology in the study of hematological malignancies help leukemia, lymphoma and other types of more in-depth, more accurate guidance and prognosis of treatment is more practical significance.