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目的:血管渗透性是维系血管功能的重要方面,而血管渗透性主要受血管内皮细胞间连接和周细胞功能状态等影响。血管内皮生长因子(VEGF)和色素上皮细胞源因子(PEDF)对血管渗透性的影响就与这些因素密切相关,并且两者也有直接或间接的联系。本文将就VEGF和PEDF与血管渗透性的关系为中心点,以血管渗透性的角度对VEGF和PEDF有一个较全面的认识。
OBJECTIVES: Vascular permeability is an important aspect of maintaining vascular function, whereas vascular permeability is mainly influenced by vascular endothelial cell connectivity and pericyte function status. The influence of vascular endothelial growth factor (VEGF) and pigment epithelial cell factor (PEDF) on vascular permeability is closely related to these factors, and the two are also directly or indirectly related. This article will VEGF and PEDF and vascular permeability as the central point of vascular permeability in terms of VEGF and PEDF have a more comprehensive understanding.