论文部分内容阅读
目的探讨肺炎支原体(MP)现时感染的临床特点。方法回顾性分析2003年4月至2004年4月间发现的双份血清MP抗体(颗粒凝集试验)滴度4倍及以上增长的13例MP现时感染患者的临床资料,所有患者年龄在17~34岁。结果查到MP抗体滴度4倍及以上升高的时间在病程的第6~17天;6例初次查抗体阴性。最常见的症状是发热(13/13)、咳嗽(11/13)、咽痛(5/13)、轻度头痛(5/13);均无鼻塞、打喷嚏,无病例出现皮疹、耳痛。咽部均有充血。外周血白细胞总数均不高。X线胸片诊断肺炎10例。适量大环内酯类+喹诺酮类抗生素治疗效果好,阿奇霉素与红霉素疗效无明显差异。结论MP主要感染青少年且易导致肺炎。肺外并发症少见。一次血清特异性抗体阳性不宜作为MP现时感染的临床诊断标准。
Objective To investigate the clinical characteristics of Mycoplasma pneumoniae (MP) infection. Methods Retrospective analysis of clinical data of 13 patients with MP presently infected with double serum MP antibody (particle agglutination test) titer of 4 times or more discovered between April 2003 and April 2004 was performed. All patients aged 17 ~ 34 years old. The results found that the titer of antibody to MP 4 times and above the duration of the disease in the first 6 to 17 days; 6 cases of initial antibody negative. The most common symptoms were fever (13/13), cough (11/13), sore throat (5/13), mild headache (5/13); no nasal obstruction, sneezing, no case of rash, earache . Pharyngeal congestion. The total number of peripheral white blood cells are not high. X-ray diagnosis of pneumonia in 10 cases. Moderate macrolide + quinolone antibiotics treatment effect, azithromycin and erythromycin no significant difference in efficacy. Conclusion MP mainly infects adolescents and easily lead to pneumonia. Extra-pulmonary complications are rare. A serum-specific antibody positive should not be used as clinical diagnosis of MP present infection.