论文部分内容阅读
目的:调查妇产科围手术期抗菌药物的使用情况,为抗菌药物的合理应用,促进合理用药提供参考。方法:抽取2008年妇产科手术病例327份,记录相关内容,根据《抗菌药物临床应用指导原则》等相关资料,对抗菌药物在妇产科手术中的使用进行合理性评价。结果:所有被调查的病例均使用了抗菌药物,共5大类21个品种。预防用药以术后用药为主,使用频率前5位为头孢丙烯(20.00%),替硝唑(16.03%),甲硝唑(15.93%),头孢美唑钠(10.10%),头孢曲松钠(7.58%);最常见的联用形式为头孢菌素类+硝咪唑类。结论:妇产科围手术期抗菌药物的使用在品种选择、用法用量上基本合理,但存在预防用药时机及疗程不当、联合用药不合理等问题,需加强妇产科手术中抗菌药物的合理应用管理。
OBJECTIVE: To investigate the use of antimicrobial agents during the perioperative period in obstetrics and gynecology and to provide reference for rational use of antimicrobial agents and promotion of rational drug use. Methods: 327 cases of obstetrics and gynecology operations in 2008 were collected and relevant contents were recorded. According to the “Guiding Principles of Clinical Application of Antibacterials” and other relevant data, the rational use of antimicrobial agents in obstetrics and gynecology was evaluated. Results: An antimicrobial agent was used in all the investigated cases. There were 21 varieties in 5 major categories. Prophylaxis was given mainly to patients after surgery. The top five frequency of use was cefprozil (20.00%), tinidazole (16.03%), metronidazole (15.93%), cefmetazole sodium (10.10%), ceftriaxone Sodium (7.58%); the most common form of combination of cephalosporins + nitrazoles. Conclusion: The use of perioperative antibacterials in gynecology and obstetrics is basically reasonable in terms of variety choice and dosage, but there are some problems such as the timing of improper medication and improper treatment, unreasonable combination of drugs, and the rational application of antibacterials in obstetrics and gynecology management.