Risk Factors of Cervical Carcinoma and Countermeasures against Them in Mountainous Area of Wufeng C

来源 :Wuhan University Journal of Natural Sciences | 被引量 : 0次 | 上传用户:ellen0807523254
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Cases (n=44) with squamous cell cervical cancer (SCCA) and age-matched healthy controls (n=176) were analyzed. Significant difference due to human papillomavirus (HPV) infection, ages at the first marriage, ages at the first sexual intercourse, ages at the first birth given to baby, number of gravidities, number of deliveries, Body Mass Index (BMI), education level of women and their husbands (p< 0.05) was observed. According to multivariate logistic regression analysis, four factors have entered the model (p<0.05), including HPV infection [OR (odds ratio)= 26.13, 95%CI (confidence interval)=9.40-72.60], education level of women (OR= 0.41, 95%CI=0.21-0.79), education level of spouses (OR=0.45, 95%CI=0.22- 0.94), BMI (OR= 0.73, 95%CI=0.57-0.93). Moreover, HPV infection is relative to education level of women (r=-0.14), and their spouses (r=-0.21), age at the first marriage (r=-0.20), age at the first birth given to baby (r= -0.20) and BMI (r=-0.15). Significant difference due to human papillomavirus (HPV) infection, ages at the first marriage, ages at the first sexual (Cases) (n = 44) with squamous cell cervical cancer (SCCA) and age- matched healthy controls intercourse, ages at the first birth to baby, number of gravidities, number of deliveries, Body Mass Index (BMI), education level of women and their husbands (p <0.05) was observed. According to multivariate logistic regression analysis, four factors have entered the model (p <0.05), including HPV infection (odds ratio) = 26.13, 95% confidence interval = 9.40-72.60], education level of women (OR = 0.41, 95% CI = 0.21- 0.79), education level of spouses (OR = 0.45, 95% CI = 0.22-0.94), BMI (OR = 0.73, 95% CI = 0.57-0.93) -0.14), and their spouses (r = -0.21), age at the first marriage (r = -0.20), age at the first birth to baby (r = -0.20) and BMI (r = -0.15).
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