The present study observed the effects of the non-invasive, mirror neuron system application on neurorehabilitation.In primate studies, mirror neurons have been shown to fire when the subject observes or performs a specific action, thereby allowing for observation of motor cortex activation.This activation of the mirror neuron system could serve as a treatment for stroke patients.In the present study, the combination of a mirror neuron system-based therapy was introduced for the treatment of patients with motor-deficits, who could not perform rehabilitation exercises.The results also indicate that this therapeutic method plays a positive role in emotional regulation in the same patients.