本文使用甲硝哒唑栓剂作双盲试验,对3例穿孔性阑尾炎所致的腹膜炎和非穿孔性阑尾炎术后的64例患者,于手术前后预防性从肛门直肠内栓塞甲硝哒唑;化脓、坏疽和穿孔性阑尾术后增用庆大霉素肌注。用药组无1例切口感染,对照组105例中有12例切口感染(p<0.01)。显示甲硝哒唑栓剂对预防阑尾炎切除术切口感染具有显著的疗效。 In this paper, we use ditonazole suppository as a double-blind test on three patients with perforated appendicitis caused by peritonitis and non-perforated appendicitis in 64 patients after preoperative and postoperative prophylactic embolization of metronidazole from the anorectal; suppurative , Gangrene and perforation of the appendix after gentamicin intramuscular injection. There was no incision infection in the medication group, and infection in 12 of the 105 control patients (p <0.01). It has been shown that ditadiazole suppositories have a significant effect in preventing incisional wound infection of appendicitis.