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目的 :了解原因不明的精神发育迟滞的病因。方法 :用 1∶ 1配比的病例对照方法进行研究 ,并用多因素条件L ogistic回归方法进行分析。结果 :单因素分析表明 :原因不明的精神发育迟滞除与遗传有关外 ,还与一些环境因素有关。多因素分析显示 :原因不明的精神发育迟滞主要与母孕期患病毒性疾病 (P=0 .0 0 2 ,OR=7.2 39) ,母孕期异常情况 (P=0 .0 0 3,OR=7.12 4)和母龄 (P=0 .0 0 6 ,OR=1.411)有关
Purpose: To understand the etiology of unexplained mental retardation. Methods: A 1: 1 ratio of the case-control study, and multi-factor condition L ogistic regression analysis. Results: Univariate analysis showed that the unexplained mental retardation was related to some environmental factors besides the genetic ones. Multivariate analysis showed that the unexplained mental retardation was mainly related to the prevalence of viral hepatitis in the first trimester (P = 0.002, OR = 7.239), abnormal pregnancy (P = 0.0030, OR = 7.12 4) and mother age (P = 0.060, OR = 1.411)