经皮冠状动脉成形术与冠状动脉旁路移植治疗多支冠状动脉病变的对照研究

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经皮冠状动脉成形术(PTCA)和冠状动脉旁路移植(CABG)是治疗多支冠状动脉病变广泛采用的方法。很少有资料将两种治疗结果进行直接对比。本文对152例作多支血管病变的PTCA组和134例作多支血管病变的CABG组进行对照研究。以前进行过PTCA或CABG患者除外。结果表明,两组患者之射血分数均明显降低(分别为48%±14%和53±15%,P=0.002);除左冠状动脉主干外,两组之间的主要分支(左前降支、回旋支和右冠状动脉)狭窄及单分支狭窄的分布无明显差别。行CABG组的每例患者均与行PTCA组患者进行对比分析(分别为3.9与3.7支血管,P<0.001);单支血管病变者75%是用左乳内动脉移植。经标准化评定,PTCA成功率为95%。 Percutaneous transluminal coronary angioplasty (PTCA) and coronary artery bypass grafting (CABG) are widely used in the treatment of multiple coronary lesions. There is little data to compare the two treatment outcomes directly. In this paper, 152 cases of multivessel PTCA group and 134 cases of multivessel CABG group for controlled study. Excluding PTCA or CABG patients. The results showed that the ejection fraction was significantly lower in both groups (48% ± 14% and 53 ± 15%, respectively; P = 0.002). Except for the left main coronary artery, the major branches (left anterior descending branch , Circumflex artery and right coronary artery) stenosis and distribution of single-branched stenosis no significant difference. Each patient in the CABG group was compared with those in the PTCA group (3.9 and 3.7 vessels, respectively, P <0.001); 75% of patients with unilateral coronary artery disease were transplanted with the left internal mammary artery. After standardized assessment, PTCA success rate was 95%.
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