对6例使用透皮吸收雌激素制剂的绝经后妇女使用经皮吸收孕激素凝胶,并观察孕激素吸收情况。6例体质指数均小于40,其中1例40岁,患卵巢早衰,另5例50～65岁,自然绝经1年以上。6例妇女在使用孕激素前2天先开始用0.05mg剂型的17β-雌二醇(E_2)贴膜,每周2片,持续使用4周。开始贴E_2后2天即开始外用孕激素凝胶,第1～2周,1g/d内含孕激素30mg;第3～4周,2g/d分二次用,内含孕激素60mg,涂抹于四肢及胸部皮肤。分 Percutaneous absorption of progesterone gel was applied to 6 postmenopausal women who used transdermal estrogen preparations and their progestogen absorption was observed. 6 cases of body mass index were less than 40, of which 1 case of 40 years old, suffering from premature ovarian failure, the other 5 cases 50 to 65 years of age, more than 1 year of natural menopause. Six women started to use 0.05 mg dosage form of 17β-estradiol (E2) two days before using progestin, two tablets per week for 4 weeks. 2 days after the start of E_2 topical progesterone gel started 2 days, 1 to 2 weeks, 1g / d containing progesterone 30mg; the first 3 to 4 weeks, 2g / d sub-second use, containing progesterone 60mg, smear On the limbs and chest skin. Minute