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目的：研究无明显病因弱视儿童黄斑中心凹厚度的变化，并与正常眼比较。方法对25例（49眼）无明显病因弱视儿童（研究组）及18例（36眼）正常儿童（对照组）分别进行光学相干断层扫描（OCT）检查，记录黄斑中心凹视网膜厚度，将两组数据进行比较。结果研究组和对照组儿童的黄斑中心凹厚度分别为217.43±12.44μm和222.12±16.22μm。两者相比，差异有统计学意义（<0.05）。结论无明显病因弱视儿童的黄斑中心凹视网膜厚度更薄。“,”Objective To assess the thickness of the fovea in amblyopia children without obvious cause by optical coherence tomography (OCT)and compare them with normal children . Methods OCT was performed on 25 amblyopia children (49 amblyopia eyes)with no obvious cause and 18 normal children (36 normal eyes).We The thickness of the macular fover was measured and compared with each other. Results The thickness of macular fovea in the n amblyopia group and the normal group were 217.43±12.44μm and 222.12±16.22μm respectivelyand a significant difference was found between the two groups ( <0.05).Conclusions The thickness of macular fovea of the amblyopia eyes with no ob-vious cause is thinner than that of normal eyes.