简要阐述mi RNA在肝细胞癌中的研究进展。肝细胞癌(HCC,hepatocellular carcinoma)是致死率最高的肿瘤之一,该病的现有诊疗手段效果并不理想。mi RNA是一类新的内源性非蛋白质编码的微小RNA。近20年来的研究发现,mi RNA与肝细胞癌的发生及发展密切相关,这使得mi RNA在临床应用方面呈现出广阔的研究前景。肝细胞癌特异性相关mi RNA的发现为肝细胞癌基因诊断、治疗和预后提供了新的研究方向 A brief account of the progress of miRNA in hepatocellular carcinoma. Hepatocellular carcinoma (HCC, hepatocellular carcinoma) is one of the most lethal tumors, the current diagnosis and treatment of the disease is not effective. mi RNA is a new class of endogenous non-protein-coding microRNAs. Nearly 20 years of research found that mi RNA is closely related to the occurrence and development of hepatocellular carcinoma, which makes miRNA has a broad research perspective in clinical application. The discovery of hepatoma-specific miRNAs has provided a new direction for the diagnosis, treatment and prognosis of hepatocellular carcinoma