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目的： 分析消化道溃疡大出血手术治疗后引发血小板减少症（ＴＣＰ） 的原因及临床意义。方法： 分析１９８６ 年３ 月～１９９５ 年１２ 月间因上消化道出血入住日本医科大学急救中心、并接受紧急手术治疗的６０ 例患者出现ＴＣＰ 的原因。结果： 经历大量输血或休克后的患者，术后ＴＣＰ 的发生明显增高； 术后ＴＣＰ 的严重程度与继发感染、多脏器功能衰竭及死亡相关。结论： 上消化道溃疡大出血患者手术止血后普遍存在ＴＣＰ， 其原因主要有大量输血和休克；术后ＴＣＰ 的程度与患者的预后有关， 术后血小板水平可做为预后指标。
Objective: To analyze the causes and clinical significance of thrombocytopenia (TCP) after surgical treatment of peptic ulcer bleeding. Methods: From March 1986 to December 1995, 60 patients with upper gastrointestinal bleeding admitted to the Japan Medical University Emergency Center and undergoing emergency surgery were analyzed for the cause of TCP. Results: After experiencing a large number of blood transfusions or shock, the incidence of postoperative TCP was significantly increased. The severity of postoperative TCP was associated with secondary infection, multiple organ failure and death. CONCLUSIONS: TCP is common in patients with hemorrhage of upper gastrointestinal ulcer due to hemostasis after surgery. The main causes of this problem include massive blood transfusion and shock. The degree of postoperative TCP is related to the prognosis of patients. Postoperative platelet level can be used as a prognostic indicator.