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应用免疫组化方法，对肺鳞癌ＥＧＦｒ的表达进行研究，并探讨其与淋巴结转移及预后的关系。２９例肺鳞癌组织均有ＥＧＦｒ表达。１３例（４４．８％）呈强阳性，１６例（５５．２％）呈弱阳性。强阳性组患者的淋巴结转移率（７６．９％）高于弱阳性组患者的淋巴结转移率（５０．８％，Ｐ＜０．０５），两组患者的生存率有明显差异（Ｐ＜０．０１）。结果提示，ＥＧＦｒ的表达与人肺鳞癌发生有一定关系，强烈表达可能是肺鳞癌恶性行为的一个重要指标。
Immunohistochemistry was used to study the expression of EGFr in lung squamous cell carcinoma and its relationship with lymph node metastasis and prognosis. Twenty-nine cases of lung squamous cell carcinoma had EGFr expression. 13 cases (44.8%) were strongly positive and 16 cases (55.2%) were weakly positive. The rate of lymph node metastasis (76.9%) was higher in the strongly positive group than in the weakly positive group (50.8%, P<0.05). The survival rate was significantly different between the two groups (P<0 .01). The results suggest that the expression of EGFr has a certain relationship with the occurrence of human lung squamous cell carcinoma, and strong expression may be an important indicator of the malignant behavior of lung squamous cell carcinoma.