难治性哮喘,系指各种治疗无效,非常不容易根治和缓解的支气管哮喘,多为依赖激素的重症哮喘。本文就我院收治的3例难治性哮喘的诊断与治疗谈几点体会。病例介绍例1:郑某,女,32岁。患者自幼出现哮喘发作,近四年来每次发作需住院治疗方能缓解。1987年5月31日再次发作4小时入院。体检:精神萎靡,端坐体位,大汗淋漓,口唇四肢末端紫绀,心率108次,两肺满布哮鸣音。实验室检查:PaCO_2=7.4KPa,PaO_2=7.0KPa,pH=7.495,一秒钟用力呼气肺活量 Refractory asthma, refers to a variety of treatment is invalid, very easy to cure and relieve bronchial asthma, mostly hormone-dependent severe asthma. This article admitted to our hospital 3 cases of refractory asthma diagnosis and treatment talk about a few experiences. Case introduction Example 1: Jeong, female, 32 years old. Patients with asthma attack since childhood, each episode of the last four years required hospitalization can ease. May 31, 1987 attack again 4 hours admission. Physical examination: apathetic, sitting posture, sweating, lips extremities cyanosis, heart rate 108 times, both lungs covered with wheeze. Laboratory tests: PaCO_2 = 7.4KPa, PaO_2 = 7.0KPa, pH = 7.495, forced expiratory volume in one second