鼻咽癌在中国华南地区有较高的发病率,但其病因至今没有明确。EB病毒感染、家族遗传、环境、饮食等都被认为是可能的原因。鼻咽癌家族聚集病例有不少文献报道,但是父母子女同患报道少见。本文报道的是一家夫妇及其子女共6人有5人患鼻咽癌,只最小的女儿目前没有发现患病。1临床资料 Nasopharyngeal carcinoma in southern China has a high incidence, but its etiology has not been clear. Epstein-Barr virus infection, familial inheritance, environment, diet, etc. are all considered as possible causes. There are many cases of NPC family aggregation reported in the literature, but parents and children with the reports of rare. This article reports that a couple and their children a total of 6 people have 5 people suffering from nasopharyngeal carcinoma, only the youngest daughter has not found the disease. 1 clinical data