论文部分内容阅读
目的:探讨2型糖尿病患者右束支传导阻滞(RBBB)与非酒精性脂肪性肝病(NAFLD)是否存在一定的相关性。方法:选择2018年3月至2019年7月于郑州大学第五附属医院住院的226例已确诊为2型糖尿病患者的相关资料进行回顾性分析。根据心电图检查结果，分为RBBB组(n n＝58)和非RBBB组(n n＝168)。收集两组患者的一般临床资料，且均于入院次日清晨空腹抽取肘静脉血检测血脂、肝功能、肾功能、凝血功能等相关指标。NAFLD的诊断基于超声检查。对可能影响2型糖尿病患者RBBB的因素进行logistic回归分析。n 结果:226例2型糖尿病患者中，男127例(56.2%)，女99例(43.8%)。RBBB组男性、年龄、2型糖尿病病程、高血压、纤维蛋白原(FIB)、血肌酐(SCr)、谷丙转氨酶(ALT)、NAFLD构成比高于非RBBB组(n P<0.05)。RBBB组总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)、白蛋白(ALB)水平低于非RBBB组(n P<0.05)。Logistic回归分析：2型糖尿病患者RBBB危险因素有男性(n OR＝2.736，95% n CI：1.075～5.251，n P＝0.032)、年龄增长(n OR＝1.049，95% n CI：1.009～1.090，n P＝0.016)、SCr水平升高(n OR＝1.045，95% n CI：1.021～1.070，n P<0.001)以及NAFLD(n OR＝2.834，95% n CI：1.166～6.891，n P＝0.022)。n 结论:NAFLD与2型糖尿病患者RBBB风险增加可能相关。“,”Objective:To investigate whether there is a correlation between right bundle branch block (RBBB) and nonalcoholic fatty liver disease (NAFLD) in patients with type 2 diabetes mellitus.Methods:A retrospective analysis of 226 patients with type 2 diabetes mellitus who were admitted to the Fifth Affiliated Hospital of Zhengzhou University from March 2018 to July 2019 was performed. According to the results of electrocardiogram examination, they were divided into RBBB group (n n=58 patients) and non-RBBB group (n n=168 patients). The general clinical data of the two groups of patients were collected, blood lipids, liver function, renal function, coagulation function and other related indicators were measured on the fasting of the next morning. The diagnosis of NAFLD is based on ultrasound. Logistic regression analysis was performed on factors that may affect RBBB.n Results:Of the 226 patients with type 2 diabetes mellitus, 127 (56.2%) were male and 99 (43.8%) were female. The composition of male, age, diabetes duration, hypertension, fibrinogen (FIB), serum creatinine (SCr), alanine aminotransferase (ALT), and NAFLD in the RBBB group was higher than that in the non-RBBB group (n P<0.05). The levels of total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C) and albumin (ALB) in the RBBB group were lower than those in the non-RBBB group (n P<0.05). Logistic regression analysis showed that male (n OR=2.736, 95% n CI: 1.075-5.251, n P=0.032), advanced age (n OR=1.049, 95% n CI: 1.009-1.090, n P=0.016), higher serum creatinine levels (n OR=1.045, 95% n CI: 1.021-1.070, n P<0.001), and NAFLD (n OR=2.834, 95% n CI: 1.166-6.891, n P=0.022) were independent risk factors of RBBB in patients with type 2 diabetes mellitus.n Conclusions:NAFLD may be associated with an increased risk of right bundle branch block in patients with type 2 diabetes.