论文部分内容阅读
目的:建立温郁金微量元素的测定方法,客观评价温郁金中微量元素对长期服用患者的健康影响。方法:用浓硝酸微波消解处理样品,ICP-OES法测定温郁金生品与炮制品中As、Ca、Cd、Cu、Fe、Hg、Mn、Pb 8种微量元素的含量,并对温郁金中微量元素进行健康风险评价。结果:温郁金生品与炮制品中重金属Cu、Cd、As和Pb含量均符合标准,Ca、Fe、Mn元素含量丰富,均不含Hg,危害指数(HI)范围在0.601-1.955。温郁金生品与炮制品中Ca和Cd元素的含量在炮制前后存在显著性差异(P<0.01,P<0.05),其他微量元素含量变化不大。除瑞安沙洲外,其余5个产地的温郁金炮制品均不具有健康风险。而除瑞安固前外,其余5个产地的温郁金生品均具有一定的非致癌健康风险。结论:该测定方法具有良好的准确度和精密度,为温郁金的药材质量控制提供了依据。
OBJECTIVE: To establish a method for the determination of trace elements in warm turmeric and objectively evaluate the effects of trace elements in warm turmeric on the health of patients under long-term use. Methods: The contents of As, Ca, Cd, Cu, Fe, Hg, Mn and Pb were determined by microwave digestion with concentrated nitric acid. ICP-OES method was used to determine the contents of trace elements Conduct health risk assessment. Results: The contents of heavy metals Cu, Cd, As and Pb in the crude and processed products of Wenyujin were all in accordance with the standard. The contents of Ca, Fe and Mn were rich, all of them were free of Hg. The hazard index (HI) ranged from 0.601 to 1.955. The content of Ca and Cd in the crude and processed products of the warm tulip had significant difference before and after processing (P <0.01, P <0.05), while the contents of other trace elements did not change much. In addition to Shui On Sha Chau, the remaining five places of origin do not have health risks of health products. In addition to the former Ruian solid, the remaining five origin of warm tulip products have a certain non-carcinogenic health risks. Conclusion: The method has good accuracy and precision, and provides the basis for the quality control of Radix U. versicolor.